Words similar to cysrs
Example sentences for: cysrs
How can you use “cysrs” in a sentence? Here are some example sentences to help you improve your vocabulary:
In four of the six cases described (CysRS, DHPS, TS and MP), such evidence was obtained by computational methods.
An important corollary of these surprising findings is a rapid divergence of the MJ1477 family from CysRS, such that all the catalytic and otherwise functionally important residues characteristic of this enzyme, and also present in other class I aaRSs, have changed.
It has been shown that M. jannaschii ProRS, a class II synthetase that is unrelated to the class I CysRS, substituted for the missing CysRS activity [ 15, 16, 17].
Furthermore, MJ1477 and its orthologs do not have the accessory domains found in all known CysRS, namely the DALR domain (named after a distinct amino-acid signature), which is shared by aaRSs of several specificities, and another domain specific to CysRS [ 19].
This prediction was then validated experimentally by showing that MJ1477 had CysRS activity in vitro and that an ortholog of MJ1477 from D. radiodurans, DR0705, complemented a CysRS deficient, temperature-sensitive, lethal E. coli mutant strain [ 18].