Words similar to cysrs

Example sentences for: cysrs

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This prediction was then validated experimentally by showing that MJ1477 had CysRS activity in vitro and that an ortholog of MJ1477 from D. radiodurans, DR0705, complemented a CysRS deficient, temperature-sensitive, lethal E. coli mutant strain [ 18].
In four of the six cases described (CysRS, DHPS, TS and MP), such evidence was obtained by computational methods.
This protein and its orthologs (direct evolutionary counterparts related by vertical descent from a common ancestor) from the bacteria Thermotoga maritima and Deinococcus radiodurans were identified as 'distant orthologs' of the Bacillus subtilis CysRS by using a computational method specifically designed to detect distantly related orthologs [ 18].
It has been shown that M. jannaschii ProRS, a class II synthetase that is unrelated to the class I CysRS, substituted for the missing CysRS activity [ 15, 16, 17].
Therefore we are forced to conclude that MJ1477 and its homologs are not related to CysRS and there is nothing in the computational analysis of these proteins that would point to an aaRS activity.