Example sentences for: cul

How can you use “cul” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mouse Cul1 overexpression in Drosophilaleads to reduced SCF function

  • Since E2F is normally degraded prior to S phase, the overlap in staining suggests that the partial suppression of Cul1 caused by mCul1 expression slowed E2F destruction to the point that it persisted briefly in S phase.

  • Similarly, limitations of Cul1 function in other organisms also uncovered the disproportionate importance of particular substrates.

  • NEDD8 modification stimulates SCF-dependent substrate ubiquitylation in vitro [ 2, 3, 4], and mutant CUL1 resistant to NEDD8 modification is defective in vivo [ 5].

  • The stage and generality of the defects make analysis of the Cul1 mutant phenotype particularly difficult.


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