Words similar to ctx
Example sentences for: ctx
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When individual Z scores of CTX were calculated for the metastatic breast cancer patients compared with the non-metastatic patients, the α LCTX form and the α L/α DCTX ratio showed the highest average increases in accordance with the ability of the α LCTX levels and the α L/α DCTX ratio to most sensitively reflect alterations in the balance between the anabolic and catabolic processes of bone turnover (Fig.
The urinary concentration of all four CTX isoforms was initially measured in reference populations of healthy premenopausal and postmenopausal women.
Measurement of CTX isoforms by immunoassay analysis
It has been shown that in Paget's disease of bone, a condition characterised by a localised upregulation of bone turnover, there is a significant increase in the ratio between the native peptide form of CTX (α L) and the age-modified forms (β L, D-isoaspartyl peptide and α D) [ 9 ] . The use of CTX ratios may thus be indicative of the significant decrease in the residence time and therefore the average age of the resorbed bone collagen type I fragments in Pagetic patients [ 9 ] . This indicates that perturbations in the normally well-regulated process of bone turnover can result in changes in the half-life of collagen type I within the bone matrix.
CTX fragments derived from newly synthesised collagen are of the native peptide form ( L-aspartyl peptide [α L]), where the aspartic acid residue (D 1211) is on the L-enantiomeric form and is linked to the glycine residue (G 1212) through a peptide bond.
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