Example sentences for: crystallography

How can you use “crystallography” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mutagenesis [ 14 ] , X-ray crystallography [ 16 40 ] , and stereochemical analysis [ 41 ] indicate that His96 is the nucleophile that attacks the α-phosphate of Fhit substrates.

  • Target sequences related to proteins that have conformations determined by experiment (X-ray crystallography or NMR) were candidates for comparative modelling.

  • Despite the fact that p51 shares an identical amino acid sequence with the N-terminal portion of p66, the two subunits assume different global folding patterns in the formation of the asymmetric heterodimer [ 9 ] . Structural determination through X-ray crystallography has revealed that the p66 subunit of HIV-1RT has its polymerase domain in an "open" conformation, with its subdomains forming a large cleft which accommodates DNA.

  • The structure of this 67 kDa domain has been determined by X-ray crystallography to be torus-like, indicating the need for protein conformational change for strand passage to take place after DNA cleavage [ 4 ] . Relaxation activity requires the presence of the Zn(II) binding tetracysteine motifs [ 5 ] found between the 67 kDa N-terminal domain (Top67) and the 14 kDa C-terminal single-stranded DNA binding domain (Figure 1).

  • Figure 2shows a multiple sequence alignment which highlights conserved amino-acid residues in the *AroQ subfamily in relationship to the homologous residues that have been shown by X-ray crystallography [ 6] to be located in the active site of the AroQ domain of E. coli AroQ•PheA.


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