Words similar to crystallographic
Example sentences for: crystallographic
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In the center of this region is a critical glycine residue that is thought to play a role in establishing a hairpin loop [ 12 ] . Recent x-ray crystallographic data obtained from an ACh binding protein (AChBP) shows a loop structure in this region resulting from a 3 residue turn containing a glycine homologous to G147 of the 5-HT 3 R. On either side of this putative turn region are residues that have been identified as important to receptor binding [ 12 13 14 15 16 17 18 ] . The formation of this loop structure brings amino acids on either side of glycine into close proximity and may form a binding pocket that will accommodate one or more functional groups.
X-ray crystallographic analysis infers specific amino acid-nucleotide contacts, but does not by itself allow a clear definition of their individual contributions to RNA-binding and translational repression.
On the basis of deduced amino-acid sequences and one crystallographic model [ 27], plant AQPs seem to include the same general structural motifs that have been detected in mammalian and bacterial AQPs.
This conformer was assigned a low population in the multi-conformational analysis of Taxol in chloroform [ 12 ] , used in the fitting of the electron crystallographic density of the β-tubulin/Taxol complex in zinc-stabilized sheets, and ultimately assessed as the binding conformation for Taxol in this structure.
S. maltophilia is an important pathogen in nosocomial infections of immunocompromised patients suffering from cancer, cystic fibrosis, drug addition, AIDS and in patients with organ transplants and on dialysis [ 30 31 32 ] . This organism is inherently resistant to most antibiotics due to its low outer membrane permeability [ 33 ] and to β-lactam containing antibiotics due to the production of a chromosomally expressed group 2e β-lactamase (L2) and a group 3c β-lactamase (L1) [ 34 35 ] . L1 has been cloned, over-expressed, and partially characterized by kinetic and crystallographic studies [ 36 37 ] . The enzyme exists as a homotetramer of ca. 118 kDa in solution and in the crystalline state.
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