Example sentences for: cross-reacts

How can you use “cross-reacts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Gleevec has been shown to induce clinical, hematological and molecular remissions for CML patients [ 4 ] . It cross-reacts with two other important growth factor receptors containing tyrosine kinase domains, c-kit and PDGF receptors, that play important roles in growth and proliferation of a variety of cell types [ 5 ] . C-kit (also known as CD117) is frequently mutated in gastrointestinal stromal tumor (GIST), and the mutated c-kit shows higher tyrosine kinase activity.

  • Gleevec was designed to inhibit the BCR-ABL tyrosine kinase, and it cross-reacts with c-kit and PDGFR [ 5 ] . In non-small cell lung cancer, BCR-ABL expression has never been reported, and it is unlikely that BCR-ABL fusion protein plays any role in lung cancer.

  • The anti-human myocilin antibody 129 used in these studies (generated to human amino acids 156-171 [ 12 17 ] ) cross-reacts with rabbit and monkey myocilin.


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