Words similar to cross-reactive
Example sentences for: cross-reactive
How can you use “cross-reactive” in a sentence? Here are some example sentences to help you improve your vocabulary:
Finally, we show that the variant induces broadly cross-reactive IgG antibodies, and that priming of animals with the variant protein results in higher titers of antigen-specific antibody upon subsequent immunization with the parent enzyme.
As a result, age-specific antibody concentration data for any given serotype are “contaminated,” to a greater or lesser degree, by cross-reactive antibodies with other specificties.
We confirmed the spatial distribution of NF-κB using a polyclonal goat anti-NF-κB p50 antibody (C-19) (Santa Cruz Biotechnology); this antibody has been shown to react with mouse p50 or p105; it is not cross-reactive with NF-κB p52, p65/RelA or p100.
Proteoglycan-induced arthritis (PGIA) is a novel autoimmune murine model that is induced by systemic immunization of BALB/c mice with cartilage proteoglycans [ 12 13 ] . The development of PGIA is based on the cross-reactive immune response between immunizing human and mouse (self) cartilage proteoglycans in genetically susceptible BALB/c mice [ 12 13 ] . Several lines of evidence indicate T-cell involvement in the pathogenesis of PGIA.
This is especially relevant to the design of subunit vaccines for malaria and schistosomiasis where high titers of high affinity antibodies are usually the best defence against invading organisms [ 11 16 24 ] . Creating T cell epitopes in expressed proteins has been demonstrated here for Hartley strain guinea pigs, and for various inbred strains of mice [ 37 38 ] . Interestingly, the introduction of T cell epitopes from a hen-egg lysozyme or ovalbumin into mouse TNF-alpha also resulted in an increased cross-reactive antibody response in mice [ 38 ] . However, the protein construct was no longer cytotoxic for L929 cells, suggesting that the modified protein was not in the correct tertiary configuration.
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