Example sentences for: crm

How can you use “crm” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 24 cells and primary mouse hepatocytes, through activation of the Fas receptor in a FasL-independent manner [ 19 25 ] . Moreover, GCDCA was demonstrated to activate both initiator and effector caspases, and that the apoptotic response can be blocked by Crm A, a caspase 8 inhibitor [ 25 ] . The mechanism by which bile acids stimulate the activation of Fas receptor remains unclear.

  • Furthermore, treatment of wild-type GFP-N200 with CRM1/exportin specific inhibitor Leptomycin B (LMB) also causes the protein to be localized exclusively in the nucleus (Fig 6B).

  • On the other hand, the truncated coiled-coil domain in GFP-N200 is unable to shield the NES from binding to CRM1/exportin.

  • These results confirmed the identified sequence ( L AN V N L M L E LL ) within the coiled-coil domain of mammalian COP1 as a likely CRM1/exportin specific NES.


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