Example sentences for: cre-mediated

How can you use “cre-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cre-mediated deletion of the pgk promoter results in the cells reverting to G418 sensitivity while retaining the Neo gene.

  • Cre-mediated targeting of single copy transgenes to specific genomic sites that have previously been marked by loxP elements has also been described both in somatic cells and more recently in ES cells using a double LoxP targeting strategy [ 22, 23].

  • Two transgenic strains [ 18, 19] use the β-actin promoter/CMV enhancer to express EGFP following Cre-mediated excision of a stop sequence, and in one of these, lacZ is expressed prior to the Cre-mediated excision event.

  • The availability of different Cre reporter strains will be valuable, not only because of the advantages of different reporter proteins, but also because the efficiency of Cre-mediated excision may be dependent on the target locus.

  • Step 2 is rapid and straightforward because Cre-mediated recombination is extremely efficient.


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