Example sentences for: covalently

How can you use “covalently” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In ChIP, whole cells are treated with formaldehyde to covalently link DNA and associated proteins, and the resulting mix is fragmented by sonication.

  • Majority of the bacterial HNOB domain proteins are predicted to covalently bind heme.

  • Sulfo-NHS-LC-biotin was used to attach biotin moieties, covalently, to the primary amino groups of poly- D-lysine on the solid surface.

  • After covalently coupling to 96-well plates, AFA were detected by enzyme-linked immunosorbent assay (ELISA) as previously described [ 1, 5].

  • For example, oligodeoxyribonucleotide probes can be covalently attached to a surface [ 10 ] , synthesized in situ [ 11 12 13 ] , or retained via electrostatic interactions with a positively charged surface [ 14 ] . A recent study examining the effect of mismatches along the length of in situ synthesized 60 mer oligodeoxyribonucleotides demonstrated a lack of an effect of mismatches for the first ten to fifteen bases at the 3' (surface) end of the oligodeoxyribonucleotide, suggesting that these bases may not be accessible during the hybridization reaction [ 12 ] . Other problems may exist when oligodeoxyribonucleotides are adsorbed to a positively-charged surface.


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