Words similar to covalently
Example sentences for: covalently
How can you use “covalently” in a sentence? Here are some example sentences to help you improve your vocabulary:
The forward primer was synthesized with one of three fluorescent dyes - HEX (green), NED (yellow), or 6-FAM (blue) (Table 2), covalently bound to the 5' end of the primer (Applied Biosystems, Foster City, CA).
We previously showed that biotin moieties can be attached covalently to the outer surface of adenoviral vectors without appreciable effect on their infectivity under carefully controlled biotinylation conditions [ 10 11 ] . Such biotinylated viral particles could be attached, specifically and stably, to a solid surface on which (strept)avidin is covalently immobilized (avidin- or streptavidin-coated solid surface).
For example, oligodeoxyribonucleotide probes can be covalently attached to a surface [ 10 ] , synthesized in situ [ 11 12 13 ] , or retained via electrostatic interactions with a positively charged surface [ 14 ] . A recent study examining the effect of mismatches along the length of in situ synthesized 60 mer oligodeoxyribonucleotides demonstrated a lack of an effect of mismatches for the first ten to fifteen bases at the 3' (surface) end of the oligodeoxyribonucleotide, suggesting that these bases may not be accessible during the hybridization reaction [ 12 ] . Other problems may exist when oligodeoxyribonucleotides are adsorbed to a positively-charged surface.
In ChIP, whole cells are treated with formaldehyde to covalently link DNA and associated proteins, and the resulting mix is fragmented by sonication.
Antisera were screened for their ability to detect the immunizing peptide and were immunoaffinity-purified with columns of the recombinant fragment covalently bound to a Affi-Gel 15 matrix (Bio-Rad, Hercules, CA).
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