Words similar to cosuppression
Example sentences for: cosuppression
How can you use “cosuppression” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, L91 is a 'single T-DNA' locus that causes homozygosity-dependent cosuppression of its GFP-COP1 transgene and of the endogenous COP1 gene at the rosette stage of development (type L=late silencing), which in turn results in a characteristic dwarfing and other aspects of a cop1 -like phenotype [ 28 ] . In contrast, E82 (type E=early) is an oligomeric T-DNA locus that causes homozygosity-dependent COP1 endogene silencing at the seedling stage, in particular deetiolation in dark-grown seedlings.
The experimental strategy of monitoring heritable epialleles via their effect on visible cosuppression patterns has been pioneered in the chalcone synthase (CHS) family of petunia and Arabidopsis [ 4 10 30 ] . For comparison, CHS trans-silencing offers exquisite sensitivity, in part due to the cell autonomy of its pigmentation phenotype, whereas COP1 essentially yields a whole-plant phenotype.
Because L91' and E82' no longer cause COP1 cosuppression, it was easy to monitor the interaction by following the cosuppression phenotypes of the naive E82 and L91 loci.
A legend for scoring the cop1 -like cosuppression and GFP-COP1 transgene silencing patterns is shown in Fig.
The stochastic nature of gene silencing has been documented on numerous occasions, e.g. [ 9 21 ] , including in one of the initial descriptions of cosuppression [ 22 ] . However, with specific regards to epigenetically active transgene loci, it is often not transparent whether their silencing behavior was stable over successive generations, nor when and how individual loci acquired their epigenetic activity.
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