Example sentences for: costimulation

How can you use “costimulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Using CD81 nullmice, CD81 was found to be required for effective Th2, but not Th1, immune responses [ 20 21 22 23 ] . But CD81 has also been found to generally costimulate T cell responses in mouse [ 16 ] and human [ 17 ] . Thus, the costimulation of T cell cytokine production by CD81 need not necessarily be biased towards Th2 cytokines.

  • This indicates that IL-4-producing cells had divided, on average, more times with CD81 costimulation than without.

  • There was no preferential costimulation of cells producing IL-4 versus IFNγ or IL-2.

  • Thus, CD81 signalling provides short-term costimulation of cells producing Th1 or Th2 cytokines, but results in a disproportionate increase in Th2 cytokine-producing cells during long-term activation.

  • [ 17 ] , CD81 costimulation was also found to increase SEB-specific proliferation, as measured by BrdU incorporation (data not shown).


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