Example sentences for: costimulation

How can you use “costimulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 17 ] , CD81 costimulation was also found to increase SEB-specific proliferation, as measured by BrdU incorporation (data not shown).

  • Specific CD98-integrin interaction occurs in the context of low density protein-lipid microdomains, possibly resembling lipid rafts [ 34 35 ] . Several important signaling molecules, including activated TCR, LAT and LCK are present in organized raft-type microdomains, and integrity of these microdomains is necessary for T cell receptor signal transduction [ 36 37 ] . Our present discovery that β1 integrins specifically associate with CD98 in lipid microdomains helps to explain the functional connections between β1 integrins and CD98 during T cell costimulation, monocyte fusion, and elsewhere.

  • Thus, direct ligation of CD81 on T cells was sufficient to induce costimulation of T cell activation.

  • A major mechanism of peripheral tolerance induction appears to involve the recognition of tolerizing antigens by T cells in the absence of costimulation [ 19].

  • In this report, an attempt is made to reconcile the findings of general T cell costimulation versus specific Th2 biasing by CD81 in human T cells.


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