Words similar to costimulation

Example sentences for: costimulation

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In conclusion, CD81 costimulation appears to have multiple effects on T cells, including costimulation of Th1 and Th2 cytokine production in short-term assays, and preferential induction of Th2 cell proliferation in long-term cultures of human memory T cells.
To determine whether costimulation through human CD81 affected these early activation events, peripheral blood cells from normal CMV seropositive donors were incubated for 6 h with a superantigen, SEB, or the viral antigen, CMV, in the presence or absence of an agonistic anti-CD81 mAb, 5A6.
However, during longer-term stimulation of T cells, the presence of CD81 costimulation leads to a disproportionate increase in IL-4-producing cells.
A major mechanism of peripheral tolerance induction appears to involve the recognition of tolerizing antigens by T cells in the absence of costimulation [ 19].
As seen in Figure 6A, the percentage of IL-4-producing cells increased preferentially over time in long-term anti-CD3 stimulations that received CD81 costimulation, relative to stimulations in the absence of anti-CD81 mAb.