Words similar to costimulation

Example sentences for: costimulation

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A major mechanism of peripheral tolerance induction appears to involve the recognition of tolerizing antigens by T cells in the absence of costimulation [ 19].
To determine whether costimulation through human CD81 affected these early activation events, peripheral blood cells from normal CMV seropositive donors were incubated for 6 h with a superantigen, SEB, or the viral antigen, CMV, in the presence or absence of an agonistic anti-CD81 mAb, 5A6.
Although CFSE content was equal in all cells on day 0 (Figure 6B), the mean level of CFSE fluorescence of IL-4-producing cells became lower over time in the presence of CD81 costimulation versus anti-CD3 stimulation alone (Figure 6Band 6C).
This indicates that IL-4-producing cells had divided, on average, more times with CD81 costimulation than without.
In this report, an attempt is made to reconcile the findings of general T cell costimulation versus specific Th2 biasing by CD81 in human T cells.