Example sentences for: cosmids

How can you use “cosmids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Bam HI/ Eco RI fragment of the M. tuberculosis H37Rv insert of the recovered plasmid was used as a probe in colony blots to find cosmids in the E. coli (pYUB178::H37Rv) library.

  • The PCR product was used as a probe for colony blots to find cosmids in the E. coli (pYUB178::H37Rv) library carrying at least a portion of the cosmid integrated in the sur2 clone.

  • In this study, the enrichment process resulted in the isolation of two strains containing small, integrated plasmids rather than the expected 30-50 kb cosmids [ 20 ] . Small plasmids corresponding to the integrated ones were present in the original E. coli (pYUB178:H37Rv) cosmid library.

  • Strains carrying different cosmids should exhibit a different pattern of hybridizing bands because of the presence of different M. tuberculosis H37Rv inserts.

  • Because the cosmids integrate into the mycobacteriophage L5 attachment site in the M. smegmatis genome, a single copy of the M. tuberculosis DNA is maintained in the M. smegmatis transformants [ 20 ] .


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