Example sentences for: cortisol

How can you use “cortisol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The mean basal cortisol level was 47.

  • Mutations in MYOC have been shown to be causative for primary open angle glaucoma (POAG) [ 1 2 3 ] . Glucocorticoids have been implicated in ocular hypertension and glaucoma due to increased plasma cortisol levels [ 4 5 ] and altered cortisol metabolism [ 6 7 ] in POAG patients and from the increased risk of developing POAG in steroid-responsive patients [ 8 9 ] . Myocilin has been shown to be upregulated in glucocorticoid-treated human trabecular meshwork (TM) cells [ 10 11 ] , and there is variable evidence for increased MYOC expression in glaucomatous individuals [ 12 13 14 ] . In addition, glaucoma patients have a higher chance of responding to steroids than non-glaucomatous individuals.

  • Cortisol levels and cortisol responses to ACTH

  • Basal and corticotropin (ACTH)-stimulated cortisol levels correlate with the severity of illness, and very high cortisol levels often signify a poor prognosis [ 14].

  • The WHR, a measure of central adiposity, is gaining increased use as a measure of etiologically significant obesity and is thought to be more closely related to pathology, especially coronary heart disease, diabetes mellitus and stroke [ 7 ] . The metabolic changes that accompany obesity include peripheral hyperinsulinemia, hyperglycemia and glucose intolerance, hypertriglyceridemia, decreased serum low-density lipoprotein, increased serum very low-density lipoprotein, increased serum leptin, dyslipidemia, increased serum cortisol clearance, increased serum C-peptide level, downregulation of insulin receptors and an exaggerated insulin response to an oral glucose load [ 12 13 14 15 ] . These changes, especially when they occur in early adulthood, may be of fundamental importance in the development of breast cancer [ 9 16 ] .


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