Words similar to corticosterone

Example sentences for: corticosterone

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Chronically elevated cortisol levels caused by Cushing's syndrome leads to central obesity [ 1 ] while the reduction of cortisol caused by Addison's disease leads to decreased body weight [ 2 ] . Obesity in several rodent models is also associated with elevated corticosterone levels, and adrenalectomy reverses some of the phenotypes associated with these forms of obesity [ 3 4 5 6 7 ] . Furthermore, elevated corticosterone production can cause a metabolic syndrome [ 8 ] . These data suggest that reduction of glucocorticoid production might therefore constitute a plausible clinical strategy to treat obesity.
Since adrenalectomy only reduced plasma corticosterone by about 70% in the obese mice, rather than completely eliminating the steroid from circulation, it remains possible that even further reduction of corticosterone would produce an effect on diet-induced obese phenotypes.
Fasting was associated with elevated corticosterone (Fig.
This may have been the source of the modestly elevated corticosterone level seen among the Lifr null pups in the adrenalectomy group.
, Chicago, IL) and serum corticosterone was assayed by radio immunoassay (RIA) with commercial kits (ICN Biomedicals Inc., Costa Mesa CA).