Words similar to cooh-terminal

Example sentences for: cooh-terminal

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EGFP-F is a derivative of GFP that exhibits enhanced fluorescence and possesses a farnesylation signal at the COOH-terminal.
In addition to a COOH-terminal PTK domain, Btk has an NH 2 - terminal pleckstrin homology (PH) domain, a proline-rich Tec homology domain, a Src-homology 3 (SH3) domain and a Src-homology 2 (SH2) domain.
[ 18 ] . This constitutively activated Stat3 (a mutant produced by substitution of the cysteine residues within the COOH-terminal loop of the SH2 domain of Stat3) induces cellular transformation and tumor formation in nude mice [ 18 ] . The plasmids to express other coactivators (SRC-1, CBP/p300, TIF2 and PCAF) have been described elsewhere [ 29 30 ] .
The D/E-rich domain is followed by the COOH-terminal M-domain that is highly conserved and contains a set of MIDAS sequence motifs [ 9 ] .
Since K430 is located on the smaller, NH 2 -terminal lobe of the kinase domain, whereas R525 is part of the larger, COOH-terminal lobe, it is possible that the two mutations differentially affect the capacity of kinase inactive Btk to function as an adapter in the activation of PLCγ2.