Example sentences for: cooh

How can you use “cooh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Construct pGBT9/prodelHB-EGF was unable to interact with pGAD424/Fib-1C EGF#5-COOH (data not shown).

  • A clone, pGAD424/Fib-1C EGF #5-COOH, that contained calcium-binding type EGF-like modules #5-9 and the carboxyl-terminus of fibulin-1C fused to the GAL4-activation domain (see Fig.

  • The PCR products were digested with Eco RI and Sal I and ligated into the Eco RI and Sal I restriction sites of pGAD424 to produce constructs pGAD424/Fib-1C EGF#1-5 and pGAD424/Fib-1C EGF#5-COOH respectively.

  • Caution must be used with this result however, as the size of the cloned prodelHB-EGF region is small, encoding just 54 amino acids; this may have resulted in a Gal4 fusion protein in which the EGF epitopes in prodelHB-EGF are hidden by the Gal4 subunit and thus not recognized by the GAL4 fusion partner protein (GAL4/Fib-lC EGF #5-COOH).

  • The structure prediction program PhD [ 23 24 ] suggests that the COOH region of the M-domain has an α/β conformation, similar to that expected from its sequence homology to the integrin I-domain, whereas the NH 2 -extension is predicted to be largely α-helical.


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