Words similar to collagenases
Example sentences for: collagenases
How can you use “collagenases” in a sentence? Here are some example sentences to help you improve your vocabulary:
Specifically, we have focused on MMP-1 and MMP-13, interstitial collagenases that have the unique ability to initiate cleavage of the triple helix comprising the stromal collagens types I, II, and III.
DMSO for 24 hours, before harvesting total RNA and determining expression of various MMP genes, including stromelysins 1 (MMP-3), 2 (MMP-10) and 3 (MMP-11), collagenases I (MMP-1) and IV (MMP-2) and meltrins α (ADAM-12) and β (ADAM-19).
Of the MMPs, the collagenases [ 5, 6] and stromelysins [ 7] have been the best studied, and marked elevations in serum and synovial levels have been found in rheumatoid arthritis (RA) [ 8].
Furthermore, cycloheximide blocks mRNA expression of both collagenases [ 11, 16], indicating that expression of immediate early genes is required for MMP-1 and MMP-13 gene expression.
We have shown in a quantitative manner that in all three cell types, MMP-1 and MMP-13 are inducible with IL-1, and that CDDO inhibits the expression of these collagenases, with optimal inhibition being observed after 24 hours of pretreatment with CDDO.