Example sentences for: colistin

How can you use “colistin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The action of colistin is by a detergent-like mechanism, interfering with the structure and function of the outer cytoplasmic membrane of bacteria and resulting in bacterial death [ 11 13 ] . It is administered as colistin sulfomethate sodium and its hydrolysis releases the active drug.

  • For the remaining patients, colistin was introduced when culture results became available in those who had not responded to the initial empiric regimen.

  • Although our findings with colistin can be considered encouraging in comparison with previous experience, the small number of patients, the concomitant use of β-lactams, and the absence of a control group in the study do not allow for a clear verdict on the clinical effectiveness of colistin.

  • On the other hand, the moderate incidence of complications suggests that colistin may be a relatively safe choice in patients with normal renal function, at least when administered in an ICU with proper monitoring of variables that affect renal function.

  • A recent study that reported that colistin methanosulfate is less rapidly bactericidal than is colistin in P. aeruginosa [ 14 ] offers retrospective justification for the higher dosage used in our ICU.


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