Words similar to colistin

Example sentences for: colistin

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The dosage of colistin used in our study was more than double that usually recommended [ 9 10 12 ] , although much higher doses - with a parallel increase in nephrotoxicity - have been reported in the past [ 23 ] . We opted for the higher dose because of the severity of the infections being treated.
Although combinations of colistin with β-lactams are reported to be of unproven benefit [ 24 25 ] , a recent study conducted in an in vitro pharmacodynamic model [ 28 ] reported synergy with ceftazidime for P. aeruginosa sensitive to colistin but resistant to other antibiotics, including ceftazidime.
Three patients had already developed acute renal failure at the initiation of treatment with colistin and were being treated with continuous venovenous hemodiafiltration (CVVHD).
The action of colistin is by a detergent-like mechanism, interfering with the structure and function of the outer cytoplasmic membrane of bacteria and resulting in bacterial death [ 11 13 ] . It is administered as colistin sulfomethate sodium and its hydrolysis releases the active drug.
Toxicity, particularly nephrotoxicity, is an important concern with colistin.