Words similar to cofactors
Example sentences for: cofactors
How can you use “cofactors” in a sentence? Here are some example sentences to help you improve your vocabulary:
Here, transcription factors are defined as proteins which recognize and bind regulatory sites and have a potential to modulate directly or indirectly through the recruitment of cofactors the activity of the basal transcriptional apparatus of proximal genes.
This developmentally important pathway contains several proteins, including APC, Frizzled, Axin and GSK3, which act in concert to promote the proteosomal degradation of β-catenin [ 13 14 ] . When APC is rendered inactive by mutation, β-catenin levels rise and the protein moves into the nucleus where it acts with Tcf/Lef cofactors to regulate transcription of c-myc , cyclin D and other oncogenes [ 15 ] .
For each in silico deletion strain, the optimal production of the twelve biosynthetic precursors and the metabolic cofactors was also calculated to identify auxotrophic requirements and impaired functions in the metabolic network (Table 1).
There is an urgent need to follow cohorts at-risks children and adolescents to investigate cofactors acting in concert with obesity that are responsible for the early onset of risk factors for cardiovascular diseases, a phenomenon increasingly being observed in many populations.
The recent findings that members of the several different families of coactivators possess intrinsic histone acetyltransferase activity suggests that activated SHRs, and nuclear receptors in general, may also recruit these cofactors to remodel chromatin structure for better accessibility of the transcriptional machinery to DNA [ 5 6 ] .
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