Example sentences for: cofactor

How can you use “cofactor” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The tissue was stained with a mixture of 2 primary antibodies - a kinase or AKAP, and a mitochondrial marker (either anti-cytochrome c or anti-lipoic acid cofactor) - overnight at 4°C.

  • The final proof that P-TEFb is the cellular cofactor for Tat came from studies of HIV transcription in murine cells, where the introduction of the human CycT1 protein restores Tat function [12].

  • Since the interactions of Ca +2and Mg +2with proteins are difficult to study due to the lack of spectroscopic properties, vanadyl (V IV=O) 2+has been used as a probe of the ligands that compose Mg 2+, Ca 2+, and Mn 2+binding sites of several proteins, including carboxypeptidase [ 16 ] , S-adenosylmethionine synthetase [ 17 18 ] , pyruvate kinase [ 19 20 ] , and F 1 -ATPase [ 21 22 ] . This cation specifically binds to divalent cation binding sites of several enzymes, and in many cases serves as a functional cofactor [ 23 ] . Vanadyl has one axial and four equatorial coordination sites relative to the axis of the double-bounded oxygen, an arrangement that is similar to that for Ca 2+and Mg 2+.

  • ThDP serves as a cofactor for several enzymes that are found both in the cytosol (transketolase) and mitochondria (α-ketoglutarate dehydrogenase complex being the most studied example).

  • Nucleotidase activity of purified soluble CD39 with VO 2+as cofactor


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