Words similar to co-stimulation
Example sentences for: co-stimulation
How can you use “co-stimulation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus by inducing migration and interaction with EC, IL-12 regulates crucial determinants of NK cell recruitment in tissues [ 20 ] . It is believed that IL-12 plays an instrumental role in tilting the immune response in favor of T helper type 1 by generation of Th1 cells and consequently initiates CMI [ 28 ] . Since IL-12 enhances cytotoxicity and augments proliferation by antigen specific T cells and NK cells, IL-12 may facilitate antigen specific and nonspecific cytotoxic immune defense against intracellular pathogens such as M. tuberculosis . An intriguing property of IL-12 is its capacity to induce proliferation by cytolytic T cell only upon co-stimulation with antigen.
Rather, CD81 co-stimulation could only be increased over basal levels by application of an agonistic mAb, 5A6.
For example, CD98 and β1 integrins may act together during T-cell co-stimulation [ 24 ] . A genetic screen revealed that CD98 may indirectly influence integrin affinity for ligand [ 25 ] . Also, anti-CD98 mAb appeared to modulate integrin-dependent adhesion in two separate studies [ 25 26 ] . In addition, antibodies to both CD98 and α3β1 integrin promoted cell fusion [ 27 ] , and antibodies to β1 and β2 integrins blocked monocyte cell-cell fusion and aggregation functions induced by an anti-CD98 mAb [ 5 ] . Finally, like CD98, the α3β1 integrin has been implicated in amino acid transport [ 28 ] .
These results may help to explain recent reports that CD98 may modulate integrin ligand binding, adhesion, signaling, T cell co-stimulation and cell fusion functions.
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