Words similar to co-stimulation
Example sentences for: co-stimulation
How can you use “co-stimulation” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, CD98 and β1 integrins may act together during T-cell co-stimulation [ 24 ] . A genetic screen revealed that CD98 may indirectly influence integrin affinity for ligand [ 25 ] . Also, anti-CD98 mAb appeared to modulate integrin-dependent adhesion in two separate studies [ 25 26 ] . In addition, antibodies to both CD98 and α3β1 integrin promoted cell fusion [ 27 ] , and antibodies to β1 and β2 integrins blocked monocyte cell-cell fusion and aggregation functions induced by an anti-CD98 mAb [ 5 ] . Finally, like CD98, the α3β1 integrin has been implicated in amino acid transport [ 28 ] .
Rather, CD81 co-stimulation could only be increased over basal levels by application of an agonistic mAb, 5A6.
These results may help to explain recent reports that CD98 may modulate integrin ligand binding, adhesion, signaling, T cell co-stimulation and cell fusion functions.
Thus by inducing migration and interaction with EC, IL-12 regulates crucial determinants of NK cell recruitment in tissues [ 20 ] . It is believed that IL-12 plays an instrumental role in tilting the immune response in favor of T helper type 1 by generation of Th1 cells and consequently initiates CMI [ 28 ] . Since IL-12 enhances cytotoxicity and augments proliferation by antigen specific T cells and NK cells, IL-12 may facilitate antigen specific and nonspecific cytotoxic immune defense against intracellular pathogens such as M. tuberculosis . An intriguing property of IL-12 is its capacity to induce proliferation by cytolytic T cell only upon co-stimulation with antigen.