Words similar to co-activator
Example sentences for: co-activator
How can you use “co-activator” in a sentence? Here are some example sentences to help you improve your vocabulary:
The functional significance of SNIP1 degradation is apparent, since SNIP1 is a constitutive interactor and functional repressor of the master transcription co-activator CBP/p300 [ 25 ] . In the BMP signaling pathways, SNIP1 is a potent inhibitor of Smad-responsive genes via inhibiting CBP/p300 (Fig.
These genes belong to receptor, co-receptor, and co-activator pathways that are part of serine/threonine receptor tyrosine kinase, Ras/Raf/MEK/ERK (MAPK) cascade, which control proliferative and/or differentiation signals.
The fact that CCR4 has been characterized as a transcriptional co-activator has led to the speculation that nocturnin serves a similar function.
Note that the relevant transcriptional binding factor and/or co-activator for CRE (CREM and ACT) and for SRY in the adult (SRY) are testis-specific [ 37 38 ] . Future studies are necessary to determine if the transcriptional binding sites revealed by this study are functional in humans.
In some cases, transcription factors may bind cooperatively to adjacent DNA sites via direct physical interaction [ 3 4 ] . In other cases, multiple transcription factors that bind independently may recruit a common co-activator [ 5 ] , or may act independently of one another to alter gene expression in response to distinct cellular cues [ 6 ] . Recent studies have also suggested that nearby transcription factors may collaboratively compete with nucleosomes, thus enhancing the binding of individual transcription factors [ 7 8 ] . Many experiments in yeast have shown that specific pairs of factors must be bound near each other for multifactorial regulation to occur [ 7 8 9 10 ] , and it is on these spatial constraints that we focus here.
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