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Example sentences for: cncss

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To resolve these alternatives we studied the spatial distribution and conservation of spacing between CNCSs in the Drosophila genome.
First, we demonstrate that the lengths of spacer intervals separating CNCSs are non-randomly distributed in the Drosophila genome, indicating a tendency for CNCSs to be clustered in non-coding DNA.
CNCSs were identified in VISTA using a window size of 10 bp with an identity of 90% with manual post-processing to remove spurious matches at the beginning and end of the alignments.
Clusters of CNCSs are readily apparent in VISTA plots of complex gene regions with known cis -regulatory function (Figures 2and 4).
These results suggest that spacer interval sequences between CNCSs (and therefore CNCSs themselves) are functionally constrained, and provide evidence against the hypothesis that CNCSs are simply mutational cold spots.