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Example sentences for: cncs

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Using CNCS clusters to identify enhancers represents the comparative genomic analogue of efforts to predict cis -regulatory sequences by exploiting the clustering of predicted transcription factor binding sites [ 70, 71].
Nevertheless, this pattern suggests a functional relationship between cis -regulatory elements and discrete CNCS clusters.
These data quantitatively describe the pattern of non-coding conservation shown in Figures 2and 4: CNCS lengths become shorter with increasing divergence but plateau to approximately the same length in the most distant comparisons.
We show here proof of the principle that CNCS clusters can be used to identify functional enhancer sequences in the Drosophila genome (Figure 7, 8), as Ishihara et al . [ 69] have shown for CNCS clusters in the mammalian genome.
Changes in the median CNCS length reflect changes in the overall distribution of CNCS lengths in pairwise comparisons between D. melanogaster and either D. erecta, D. pseudoobscura, D. willistoni , or D. littoralis (Figure 5).