Example sentences for: clozapine

How can you use “clozapine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Clozapine abolished the electromyogram (EMG) recorded from the EUS during the rising phase of a bladder contraction before urine is voided (similar to the "guarding reflex" [ 8 9 ] ). In addition, clozapine also abolished the high frequency oscillations in the bladder pressure and accompanying bursts in the external urethral sphincter EMG, that are present during the expulsion phase of the micturition profile of the rat [ 7 ] . In the clinical literature, clozapine therapy is associated with a high incidence (up to 44% in a recent study [ 10 ] ) of urinary incontinence and enuresis.

  • Olanzapine is a newer atypical antipsychotic agent with a pharmacological profile very similar to that of clozapine [ 11 ] . In human brain tissue, olanzapine displays very high affinity for the H1 histamine receptor, high affinity for 5-HT2A and 5-HT2C receptors [ 12 ] . In addition it also shows affinity for D2, muscarinic, and alpha1 receptors, with lower affinity for alpha2, 5-HT1D and 5-HT1A receptors (Table 1 [ 12 ] ).

  • If these effects also occur in patients, they may contribute to the urinary disturbances reported following clozapine therapy.

  • Clozapine i.t.

  • Clozapine administered i.c.v at a dose of 0.5 nmoles decreased the EUS EMG to 68 ± 13.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast