Example sentences for: clozapine

How can you use “clozapine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Clozapine i.c.v, however, was not observed to abolish the bursting pattern during this phase (Fig 2), except in 1/6 animals.

  • By limiting the application site to a specific area of the central nervous system and comparing the results with our previous findings after systemic administration [ 12 ] it might be possible to determine whether the effects of clozapine are mediated at a central or peripheral level.

  • Since clozapine crosses the blood-brain barrier readily [ 14 ] , the maximum dose selected in the present experiment was restricted to the first appearance of a decrease in blood pressure as an indication of possible peripheral alpha 1 antagonism due to peripheral leakage.

  • Blockade of the external urethral sphincter in anesthetized rats results in a disappearance of the HFO from the bladder pressure recording as well as a disappearance of the bursting pattern of the EUS EMG observed during HFO [ 26 27 28 ] . In addition, there is a decreased ability of the bladder to empty as evidenced by a decreased micturition volume and an increased residual volume [ 26 27 29 ] . Therefore, inhibition of the external urethral sphincter, as was the case for the two neuroleptics in the present study and also for clozapine in our earlier study [ 7 ] , might provide an important mechanism by which the bladder is rendered less effective in emptying and therefore altering other urodynamic variables resulting in decreased micturition volume and increased residual volume in rats.

  • 5 and 50 nmoles of clozapine i.t.


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