Example sentences for: clasp

How can you use “clasp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, deletion of aIIb cytoplasmic tail completely removes the clasp and permanently activates the receptor (O'Toole et al.

  • Mutational studies provided the initial hints that disruption of the non-covalent clasp between α and β cytoplasmic tails is clearly the event within the structure of the integrin that initiates inside-out signaling.

  • Shortly thereafter, the model gained direct and strong experimental support from a structural analysis in which the membrane-proximal helices of the two subunits were found to clasp in a weak “handshake” that could be disrupted by talin or constitutively activating mutations (Vinogradova et al.

  • Although we know that the membrane-proximal clasp on the integrin cytoplasmic face controls the integrin activation, the distal side of either the α or β cytoplasmic tails may also play a role in integrin activation, since other mutations indicate that the C-terminal membrane distal region is important in regulating integrin activation via a mechanism that is yet unknown.

  • They showed that replacement of the cytoplasmic-transmembrane regions by an artificial linkage between the tails inactivates the receptor, whereas breakage of the clasp activates the receptor (Lu et al.


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