Words similar to clasp
Example sentences for: clasp
How can you use “clasp” in a sentence? Here are some example sentences to help you improve your vocabulary:
1991), whereas a particular disease mutation may only impair the clasp and partially activate the receptor (Peyruchaud et al.
They showed that replacement of the cytoplasmic-transmembrane regions by an artificial linkage between the tails inactivates the receptor, whereas breakage of the clasp activates the receptor (Lu et al.
Mutational studies provided the initial hints that disruption of the non-covalent clasp between α and β cytoplasmic tails is clearly the event within the structure of the integrin that initiates inside-out signaling.
Shortly thereafter, the model gained direct and strong experimental support from a structural analysis in which the membrane-proximal helices of the two subunits were found to clasp in a weak “handshake” that could be disrupted by talin or constitutively activating mutations (Vinogradova et al.
Although we know that the membrane-proximal clasp on the integrin cytoplasmic face controls the integrin activation, the distal side of either the α or β cytoplasmic tails may also play a role in integrin activation, since other mutations indicate that the C-terminal membrane distal region is important in regulating integrin activation via a mechanism that is yet unknown.
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