Example sentences for: cisplatin

How can you use “cisplatin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We used the IC50 concentrations for both Gleevec and cisplatin to treat A549 cells in culture, and assessed the viability of the cells by MTT assays at the different time points (Figure 4).

  • Gleevec (2 μM) and cisplatin (64 μM) both inhibited the growth of the tumor cells individually after treatment of the cells for 48 hour.

  • Cisplatin causes two types of DNA damage, DNA adducts and inter-stranded cross-linking, resulting in activation of apoptosis pathway in the target tumor cells [ 13 14 ] . Our results suggest that inhibition of tyrosine kinase activity of the potential targets by Gleevec appear to potentiate the effect of cisplatin in DNA-damage induced apoptosis in A549 cells.

  • They also received two cycles of cisplatin and 5-fluorouracil during the first and sixth weeks of irradiation.

  • The concentration of Gleevec to inhibit 50% cell growth (IC50) was estimated to be around 2-3 μM (Figure 1), whereas the IC50 of cisplatin on A549 cells was estimated to be 64-70 μM (Figure 2).


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