Example sentences for: cisplatin

How can you use “cisplatin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We sought to see if Gleevec can potentiate the cell killing effects of cisplatin, the leading chemotherapeutic drug for almost all advanced cancer patients.

  • They also received two cycles of cisplatin and 5-fluorouracil during the first and sixth weeks of irradiation.

  • Synergistic effect of Gleevec and cisplatin on A549 cells

  • Epigenetic gene silencing of the MGMT confers enhanced sensitivity to alkylating agents in cancer [ 24 25 ] . Lack of methylation, on the other hand, associates with high-risk of death [ 25 26 ] . It has been suggested that the high-levels of MGMT proteins contribute to a drug-resistant phenotype [ 27 ] . More than 90% of newly diagnosed GCTs and 70-80% of patients who present metastatic disease are cured with cisplatin-based chemotherapy [ 28 ] . However, 20-30% of the patients with metastatic disease exhibit resistance to the cisplatin curative regimen leading to high mortality in this group.

  • Gleevec (2 μM) and cisplatin (64 μM) both inhibited the growth of the tumor cells individually after treatment of the cells for 48 hour.


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