Words similar to chs
Example sentences for: chs
How can you use “chs” in a sentence? Here are some example sentences to help you improve your vocabulary:
The experimental strategy of monitoring heritable epialleles via their effect on visible cosuppression patterns has been pioneered in the chalcone synthase (CHS) family of petunia and Arabidopsis [ 4 10 30 ] . For comparison, CHS trans-silencing offers exquisite sensitivity, in part due to the cell autonomy of its pigmentation phenotype, whereas COP1 essentially yields a whole-plant phenotype.
PTGS and trans-silencing are similarly intertwined in other cases, for example in the epimutable petunia CHS41 locus [ 10 ] . PTGS often leads to DNA methylation, although primarily in coding regions [ 35 ] . However, DNA methylation of promoters, more easily aligned with transcriptional silencing, can be RNA mediated if suitable double stranded RNA versions of the promoter sequence are transcribed, either fortuitously or by design [ 36 37 38 39 40 ] . Therefore, there may be a natural tendency for PTGS loci to mature to TGS and associated trans-silencing, which in turn could prove problematic in applying PTGS in commercial plant breeding programs.
In contrast, in the PAI gene family, combining the master locus (WS ecotype PAI1/PAI4 ) with a non-allelic singlet target locus possessing 100% sequence identity (Columbia PAI2 ) resulted in methylation after two generations of heterozygous contact, and methylation became more pronounced after another two generations [ 12 ] . Likewise, in the petunia CHS gene family, interaction between an epiallele of the direct-repeat locus, CHS41, with two types of target loci, either an unlinked inverted repeat locus or a more naïve allele of CHS41, was initially additive and only became suppressive in the second generation [ 4 10 ] .
CHS Cardiovascular Health Study
CHS participants were somewhat healthier than the average older adult; however, adjustment for detailed covariates made little difference in the findings.
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