Words similar to chondrocytes

Example sentences for: chondrocytes

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This was regardless of levels of expression of the Hoxc-8 transgene (Figure 7, Panel B) which increases with increasing transgene dosage [ 1 23 ] . These data indicate that, after appropriate time in culture, transgenic chondrocytes were able to proliferate normally, at least over the 24 hours duration of the assay.
In diarthodial joints, cartilage provides a smooth surface that enables joints to articulate and to withstand compressional and shear stress [ 1 ] . Embedded in the cartilage are chondrocytes that respond to biochemical and physical stimuli to maintain this tissue.
While IL-1 promotes cartilage degradation through MMP synthesis and inhibits matrix deposition by reducing Col2A1 gene expression, TGF-β has the opposite effect on chondrocytes [ 3].
TGF-β1 expression would need to be targeted, at the appropriate levels, to the site of cartilage damage, such as through gene transfer to chondrocytes or stem cells involved in repairing the damaged tissues.
This is consistent with our previously published finding that steady-state MMP-13 mRNA levels peak 12 hours after IL-1 treatment of chondrocytes [ 11].