Words similar to chondrocytes
Example sentences for: chondrocytes
How can you use “chondrocytes” in a sentence? Here are some example sentences to help you improve your vocabulary:
We know from studies investigating the recovery of trypsin-induced homogeneous GAG depletion in young bovine cartilage that the inherent ability of chondrocytes to replenish the matrix is relatively uniform [ 14 ] . In the present study, we take advantage of the characteristic spatial heterogeneity of IL-1-induced GAG depletion to study the relative replenishment rates between regions of varying severity of GAG depletion.
Whether the elevated Ihh mRNA levels originate from increased expression in cells that make Ihh normally (prehypertrophic and hypertrophic chondrocytes) or from ectopic activation by the Hox transcription factors in proliferating cells, remains to be investigated.
In a previous study, Northern blot analysis showed that treating SW-1353 cells with 300 nM CDDO for 24 hours before treatment with IL-1 inhibited the expression of MMP-1 and MMP-13 [ 23 ] . In the present study we used quantitative real-time RT-PCR to examine the action of CDDO on the expression of MMP-1 and MMP-13 in SW-1353 cells and in two primary cultures: human primary chondrocytes and OA synovial fibroblasts.
There is disagreement over which collagenase predominates in cartilage degradation in vivo [ 10 11 ] . It is therefore of interest to find the levels of MMP-1 expressed compared with that of MMP-13 in SW-1353 and human primary chondrocytes.
In our system, the biological effects of Hox genes in chondrocytes can be modulated by external factors, and this finding points to the importance of gene-environment interactions as modulators of Hox gene function.
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