Words similar to chondrocyte
Example sentences for: chondrocyte
How can you use “chondrocyte” in a sentence? Here are some example sentences to help you improve your vocabulary:
Detailed knowledge of regulatory mechanisms in endochondral ossification will be essential for strategies to manipulate chondrocyte proliferation, differentiation and maturation in skeletal growth and development, osteochondrodysplasias and fracture healing.
Data obtained previously in our laboratory suggest that inhibition of granulosa I Kur should be associated with a +10 to +20 mV depolarization of cell resting membrane potential; block of I Ks alone decreased resting potential by +10 mV while block of both I Ks and I Kur decreased resting potential by +20 to +30 mV [ 18 ] . Most previous investigations of 4-AP effects on the resting membrane potentials of non-nerve, non-muscle cells have similarly demonstrated drug-induced depolarization [ 42 60 ] , although there is a single report showing 4-AP-induced hyperpolarization of chondrocyte membrane potential [ 62 ] .
It is also remarkable, as apparent from our cell culture results, that cells with obvious molecular differences downstream of Hoxc-8 expression can be modulated to resemble a normal chondrocyte phenotype after a few days in culture.
Other workers and ourselves have previously examined the effects of TGF-β1 gene transfer on matrix synthesis in chondrocyte cultures, demonstrating a significant stimulation in the production of proteoglycans [ 9 ] . In addition, we have demonstrated that the TGF-β1 gene was able to overcome the inhibitory effects of IL-1β on matrix metabolism in chondrocytes in culture [ 20 ] .
Sections were evaluated in a blinded manner for histologic signs of arthritis and scored as follows: 1, synovial cell proliferation, synovial hypertrophy with villus formation and/or fibrin deposition; 2, inflammation, synovitis and/or generalized inflammation; 3, cartilage disruption, chondrocyte degeneration and/or ruffling of cartilage surface and/or dystrophic cartilage; and 4, joint destruction, cartilage erosion with abundant inflammation and pannus formation with bone erosion.
Loading...