Words similar to chk

Example sentences for: chk

How can you use “chk” in a sentence? Here are some example sentences to help you improve your vocabulary:

Hus1, Rad1, Rad9 and Rad17 facilitate Rad26/Rad3-dependent phosphorylation of Chk1.
12A), the increased expression of Chk1, Chk2, and E2F1 best discriminates control from SN50-treated explants.
In fission yeast, the checkpoint rad +genes ( hus1 +, rad1 +, rad3 +, rad9 +, rad17 +and rad26 +) and chk1 +manage the sensing and transducing operations of the DNA damage checkpoint [ 1 16 ] . Current data suggest that the Rad26/Rad3-kinase complex initially senses DNA damage by an unknown mechanism [ 17 ] . This response leads to an increase in the kinase activity of the complex [ 18 ] , which phosphorylates and activates the transducing protein kinase, Chk1 [ 19 ] . Finally, Chk1 delays mitotic entry by targeting Cdc25 and Wee1, regulators of cyclin-dependent kinase activity [ 20 21 22 ] .
While phosphorylation of serines 15 and 20 of p53 are clearly dependent on the ATM and chk2 protein kinases [ 10, 11, 12, 13, 14], the kinases responsible for phosphorylation of the remaining serine residues in vivo is not clear.