Words similar to chk

Example sentences for: chk

How can you use “chk” in a sentence? Here are some example sentences to help you improve your vocabulary:

Activated chk2 can then directly phosphorylate serine 20 of p53 [ 13, 14].
Viewing the most defining proteins with altered expression, it is clearly reflective of increased apoptosis (increased Chk1, Caspase 6, E2F1), decreased cell proliferation and branching (decreased GR), and, interestingly, increased expression of diverse signal transduction pathways (Ras/Raf/ERK, JNK) to compensate for the proapoptotic signal.
From this location, the 9-1-1 complex may link the Rad26/Rad3 complex with Chk1.
While phosphorylation of serines 15 and 20 of p53 are clearly dependent on the ATM and chk2 protein kinases [ 10, 11, 12, 13, 14], the kinases responsible for phosphorylation of the remaining serine residues in vivo is not clear.
These target proteins include the c-Abl tyrosine kinase, the p53 tumor suppressor, the Chk1 and Chk2 serine/threoine kinase, the p34 subunit of replication protein A (RPA), Chk1 serine/threoine kinase and NBS1 kinase which is mutated in human autosomal recessive disease Nijmegan breakage syndrome [ 16 17 18 19 20 21 22 23 ] . Clinical characteristics of AT patients include hypersensitivity to irradiation, thymic dysplasia, immune defects and higher tendency to develop malignant tumor, suggesting that ATM function is critical in DNA damage repair and tumor suppression.