Words similar to chimeras
Example sentences for: chimeras
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First, PcrG-GAL4-AD and LcrV-GAL4-BD chimeras were coexpressed in a yeast two-hybrid assay.
This region was identified using chimeras of α 1S and α 1C [ 16 ] . Since Csk53 is present in α 1S Δ1-700 and was detected by the II-III loop antibody which is directed against the center portion of Csk53 [ 34 ] , the participation of this domain in the EC cannot be ruled-out.
Experiments used the chimeras expressed either via the pJ3H vector, or the HA-tagged chimera subcloned into the expression vector pMEXneo [ 48 ] . The oncogene v-crk and its mutants cloned into pMEXneo have been described [ 49 50 ] .
These were expanded and used to produce germline chimeras.
Although syk -deficient mice die perinatally, analysis of radiation chimeras reconstituted with fetal liver from syk -deficient mice has demonstrated a block in the transition from proB cells to preB cells, indicating that signal transduction through Syk is required for early B cell development [ 35 36 ] . Inactivation of the syk gene in the chicken DT40 B cell lymphoma leads to a loss in the activation of PLCγ2, the increase in intracellular free Ca 2+and the apoptotic response following engagement of the BCR.
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