Words similar to chimera
Example sentences for: chimera
How can you use “chimera” in a sentence? Here are some example sentences to help you improve your vocabulary:
Transient expression of the Src*/Cas(SD) in Cos-7 cells followed by analysis of total cell lysates using anti-phosphotyrosine antibodies demonstrated that while the attenuated Src kinase domain alone did not increase total cellular tyrosine phosphorylated proteins as expected, expression of the Src*/Cas(SD) fusion resulted in tyrosine phosphorylation of a protein of the expected size of the chimera, as well as other proteins (Fig.
Instead of the usual Rab1B juxtanuclear Golgi localization, the Rab1B(wt)/Rab24 chimera showed a broader cytoplasmic distribution similar to that of Rab24(wt) (Fig.
To determine if the tyrosine phosphorylated chimera could compete with endogenous Cas for binding to endogenous c-crk, we transfected either the isolated attenuated Src kinase domain as control, or the tyrosine phosphorylated Cas substrate domain (Src*/Cas(SD)) into Cos-7 cells, and immunoprecipitated endogenous c-crk (Fig.
In addition, we determined if tyrosine phosphorylation of endogenous FAK and endogenous Cas was affected by the presence of the chimera.
Instead, expression of tyrosine phosphorylated Cas SD chimera resulted in significant reduction in the number of v-crk/NIH3T3 soft agar colonies as well as their size (Fig.