Example sentences for: chimera

How can you use “chimera” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Transient expression of the Src*/Cas(SD) in Cos-7 cells followed by analysis of total cell lysates using anti-phosphotyrosine antibodies demonstrated that while the attenuated Src kinase domain alone did not increase total cellular tyrosine phosphorylated proteins as expected, expression of the Src*/Cas(SD) fusion resulted in tyrosine phosphorylation of a protein of the expected size of the chimera, as well as other proteins (Fig.

  • Instead of the usual Rab1B juxtanuclear Golgi localization, the Rab1B(wt)/Rab24 chimera showed a broader cytoplasmic distribution similar to that of Rab24(wt) (Fig.

  • To determine if the tyrosine phosphorylated chimera could compete with endogenous Cas for binding to endogenous c-crk, we transfected either the isolated attenuated Src kinase domain as control, or the tyrosine phosphorylated Cas substrate domain (Src*/Cas(SD)) into Cos-7 cells, and immunoprecipitated endogenous c-crk (Fig.

  • In addition, we determined if tyrosine phosphorylation of endogenous FAK and endogenous Cas was affected by the presence of the chimera.

  • Instead, expression of tyrosine phosphorylated Cas SD chimera resulted in significant reduction in the number of v-crk/NIH3T3 soft agar colonies as well as their size (Fig.


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