Example sentences for: chelation

How can you use “chelation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Details on study design, length of follow-up, number of patients included, patient age, presence of iron overload-related complications at study start, prior and current iron chelation (drug, route, dose), use of concomitant medication and outcome measures were extracted independently by two investigators using a standardized electronic data collection form.

  • Milligrams of fusion proteins between thioredoxin and DAZAP1 were prepared and purified on His-Bind metal chelation resins (Novagen, Madison, WI).

  • The initial step of the insertion can proceed in the presence of either Mg.ATP or a non-hydrolyzable ATP-analog and involves oligomerization of the BchD and BchI subunits to form an oligomeric ring of AAA protomers that resembles the ring structure of NSF and other AAA proteins [ 14 32 ] . The second step of the insertion involves an obligatory hydrolysis of ATP that is tightly coupled with the transfer of the chelated Mg 2+to the protoporphyrin ring by BchH [ 49 ] . Although the details differ from midasin, particularly with respect to the subunit composition of the AAA ring, this chelation reaction provides a structural model suggesting that the function of the midasin M-domain may be to regulate the ATPase activity of the AAA protomers in the pseudo-hexameric ring and thus couple ATP hydrolysis to the binding of a protein ligand at the MIDAS site.

  • Liver biopsies are neither a convenient [ 23 ] nor patient-preferred [ 2 19 25 ] means of monitoring efficacy in iron chelation therapy.

  • The catalytic domain of MHCK-C was expressed in bacteria and purified using nickel chelation chromatography as described [ 18 ] . Purified protein was injected into New Zealand White rabbits at two week intervals for a total of five injections, followed by a terminal bleed.


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