Example sentences for: chelation

How can you use “chelation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The initial step of the insertion can proceed in the presence of either Mg.ATP or a non-hydrolyzable ATP-analog and involves oligomerization of the BchD and BchI subunits to form an oligomeric ring of AAA protomers that resembles the ring structure of NSF and other AAA proteins [ 14 32 ] . The second step of the insertion involves an obligatory hydrolysis of ATP that is tightly coupled with the transfer of the chelated Mg 2+to the protoporphyrin ring by BchH [ 49 ] . Although the details differ from midasin, particularly with respect to the subunit composition of the AAA ring, this chelation reaction provides a structural model suggesting that the function of the midasin M-domain may be to regulate the ATPase activity of the AAA protomers in the pseudo-hexameric ring and thus couple ATP hydrolysis to the binding of a protein ligand at the MIDAS site.

  • Liver biopsies are neither a convenient [ 23 ] nor patient-preferred [ 2 19 25 ] means of monitoring efficacy in iron chelation therapy.

  • These compounds may have played a role in the inhibitory effect observed, probably owing to the chelation of the zinc required for the catalytic activity of venom's haemorrhagic metalloproteinases [ 45 ] . Reduction in the intensity of the effects of envenomation could also be achieved by a neutralisation of the venom peptides, polypeptides, proteins and enzymes [ 38 11 ] . There are plants used for snakebite that act by inhibiting the proteolytic activities of the venom and antagonising crotoxin-induced haemolysis, myotoxic and haemorrhagic activities of crotalid venoms [ 46 ] .

  • The deletion mutant, ΔTPR-PfPP5, was similarly cloned by PCR using a primer corresponding to the internal sequence, and purified by nickel chelation affinity chromatography.

  • The studies identified were carefully evaluated for eligibility; they were included if they (i) enrolled subjects with thalassemia major - irrespective of age at diagnosis, treatment initiation or study start nor of treatment history in terms of transfusion regimen or iron chelation; (ii) followed patients treated with either desferrioxamine administered subcutaneously or intravenously or oral deferiprone; and (iii) measured hepatic iron concentrations to evaluate treatment efficacy.


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