Words similar to chelation
Example sentences for: chelation
How can you use “chelation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Details on study design, length of follow-up, number of patients included, patient age, presence of iron overload-related complications at study start, prior and current iron chelation (drug, route, dose), use of concomitant medication and outcome measures were extracted independently by two investigators using a standardized electronic data collection form.
The deletion mutant, ΔTPR-PfPP5, was similarly cloned by PCR using a primer corresponding to the internal sequence, and purified by nickel chelation affinity chromatography.
The studies identified were carefully evaluated for eligibility; they were included if they (i) enrolled subjects with thalassemia major - irrespective of age at diagnosis, treatment initiation or study start nor of treatment history in terms of transfusion regimen or iron chelation; (ii) followed patients treated with either desferrioxamine administered subcutaneously or intravenously or oral deferiprone; and (iii) measured hepatic iron concentrations to evaluate treatment efficacy.
Liver biopsies are neither a convenient [ 23 ] nor patient-preferred [ 2 19 25 ] means of monitoring efficacy in iron chelation therapy.
The initial step of the insertion can proceed in the presence of either Mg.ATP or a non-hydrolyzable ATP-analog and involves oligomerization of the BchD and BchI subunits to form an oligomeric ring of AAA protomers that resembles the ring structure of NSF and other AAA proteins [ 14 32 ] . The second step of the insertion involves an obligatory hydrolysis of ATP that is tightly coupled with the transfer of the chelated Mg 2+to the protoporphyrin ring by BchH [ 49 ] . Although the details differ from midasin, particularly with respect to the subunit composition of the AAA ring, this chelation reaction provides a structural model suggesting that the function of the midasin M-domain may be to regulate the ATPase activity of the AAA protomers in the pseudo-hexameric ring and thus couple ATP hydrolysis to the binding of a protein ligand at the MIDAS site.
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