Words similar to checkpoint-induced

Example sentences for: checkpoint-induced

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22 rad26-GFP cells (Figure 6), so they likely resulted from Bleomycin-induced DNA damage as opposed to checkpoint-induced cell cycle arrest.
The checkpoint system in fission yeast also allows cells to recover from checkpoint-induced cell cycle arrest [ 9 39 40 ] . Together with the other Checkpoint Rad proteins, the Rad26/Rad3 complex controls this genetically defined pathway that likely regulates DNA repair activities.
These data suggest that both patterns of Rad26-GFP fluorescence (spots and speckles) occur as a result of DNA damage, as opposed to the checkpoint-induced G2/M cell cycle delay that follows Bleomycin treatment.
A mutant allele, rad26.T12 , genetically separates these functions, since rad26.T12 cells can undergo checkpoint-induced cell cycle arrest but fail to recover and lose viability [ 13 40 ] . To determine if spots and speckles are associated with these different Rad26 functions, we tagged the C-terminus of Rad26.T12 with GFP using the same primers and method that we used to tag Rad26 (see Methods).
For instance, rad26.T12 cells undergo checkpoint-induced cell cycle arrest, but lose viability upon re-entry into the cell cycle [ 40 ] . The rad26.T12 mutation acts by reducing the stability and activity of the Rad26/Rad3 checkpoint complex [ 18 ] , suggesting that cell cycle arrest requires only a pulse of Rad26/Rad3 kinase activity while recovery may require more.