Example sentences for: cerebrovascular

How can you use “cerebrovascular” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Identifying genes for polygenic ischemic stroke has been a difficult task and most human studies have employed a candidate gene approach [ 5 ] although at least one genomewide linkage scan in affected sibling pairs is on the way [ 22 ] . We propose to use a combination of a candidate gene association study and genomewide association scan in children with Hb SS at high (230 cases) or low (400 controls) risk for cerebrovascular disease as determined by their TCD velocity.

  • Visual stimulation was chosen in particular because of the known predilection of the cerebrovascular abnormalities in Fabry disease for the posterior circulation [ 7 10 ] . The lack of an increase or decrease in visual rCBF reactivity in Fabry disease suggests normal neuro-vascular coupling mechanism [ 18 19 ] .

  • We therefore believe that hidden stratification is unlikely to be a problem in our case-control study of African-American children with sickle cell disease at high or low risk for cerebrovascular disease based on their TCD values.

  • , from cerebrovascular stroke and neurotrauma) [ 1 2 3 4 5 ] and, 3) decreases the risk and delays the onset of neurological disorders such as, Alzheimer's disease [ 4 5 ] . Numerous studies indicate that estrogen is essential for optimal brain function [ 1 2 3 4 5 ] , as estrogen has been shown to increase cerebral blood flow [ 1 2 3 4 5 ] , act as an anti-inflammatory agent [ 1 2 3 4 5 ] , and enhance activity at neuronal synapses [ 1 2 3 4 5 ] . Through a variety of mechanisms, estrogen strongly influences memory and cognition; a type of cognition, which is especially dependant on gonadal hormones (i.e.

  • Fabry disease is an X-linked disorder resulting in reduced activity of the lysosomal enzyme α-galactosidase A [ 1 2 ] . This results in the systemic accumulation of D-galatosyl conjugates, particularly globotriosylceramide (Gb3) [ 3 4 ] . Although the disorder is heterogeneous, patients suffer renal, cardiovascular and cerebrovascular complications [ 4 ] . Enzyme replacement therapy has recently shown to have an effect on resting cerebral blood flow abnormalities and on other organ systems functions [ 5 6 ] . In the cerebrovascular system there is an increased incidence of stroke together with vessel ectasia [ 7 ] . This may be related to the progressive accumulation of storage material in the cerebral vessel or possibly, may be due to an abnormality of vessel function [ 8 9 ] . The cerebrovascular complications are distributed predominantly in the posterior circulation with a progressive increase over time in the posterior distribution of small vessel disease as found on T 2 -weighted images or fluid attenuated inversion recovery (FLAIR) MR [ 7 10 11 ] . It likely that such high signal lesions on MR images represent ischemic small vessel disease, however, there are no neuropathological-radiological correlative studies confirming this assumption.


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