Example sentences for: cerebrospinal

How can you use “cerebrospinal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In standard artificial cerebrospinal fluid (ACSF), a tetanic stimulation at 100 Hz, 100 μsec, 2 mA, for 200 ms (20 trains) elicited γ and β frequency population spikes, visible both with intracellular and extracellular recordings.

  • Transthyretin is specifically involved in transporting thyroxine (T4) and retinol-binding protein in cerebrospinal fluid and brain serum.

  • For example, chronic treatment with fluoxetine decreases the release of AVP from rat hypothalamic organ cultures [ 36 ] . This finding is particularly noteworthy since alterations in AVP levels in the cerebrospinal fluid have been correlated with occurrences of OCD [ 15 16 ] . The occurrence of OCD has also been correlated with increased levels of oxytocin, a neuropeptide closely related to AVP [ 37 ] . In golden hamsters, the elevation of serotonin in the anterior hypothalamus following fluoxetine treatment can inhibit the activity of the AVP system related to aggressive behavior [ 10 11 ] . The ability of microinjected AVP in the anterior hypothalamus to enhance aggressive behavior in golden hamsters is blocked by fluoxetine treatment and serotonin 5HT 1A receptor agonists [ 10 ] . The present data include AVP-stimulated flank marking in the list of behaviors suppressed by fluoxetine treatment.

  • Indeed, alterations in AVP regulation and secretion are thought to be one possible biochemical abnormality in patients with Obsessive Compulsive Disorder (OCD) [ 15 16 17 18 ] . This disorder is characterized by sudden, recurrent thoughts or images that intrude into consciousness (obsessions) driving stereotyped acts that the person feels compelled to perform (compulsions) [ 19 ] . Interestingly, patients with OCD show elevated basal levels of AVP in the cerebrospinal fluid and exaggerated plasma levels of AVP in response to hypertonic challenge [ 16 ] . Many patients with anorexia nervosa and bulimia nervosa, both compulsive eating disorders, have abnormal levels of AVP in the cerebrospinal fluid and plasma [ 15 17 ] . Pediatric patients with severe OCD have low levels of AVP in cerebrospinal fluid, while a subgroup of pediatric patients with compulsive checking rituals has elevated AVP levels [ 18 ] . Hence, there are many clinical examples of compulsive behavior associated with a perturbation in the AVP system.

  • In one patient a sample of ascitic fluid, and in other case cerebrospinal fluid (CSF) were obtained.


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