Words similar to cellularity
Example sentences for: cellularity
How can you use “cellularity” in a sentence? Here are some example sentences to help you improve your vocabulary:
Fibroblasts at glabrous sites (palms, soles) do not promote keloid formation consistent with an earlier reduction in cellularity, necessary for a normal wound healing.
Progression of granulation tissue to neodermis requires a decrease in cellularity through apoptosis of endothelial cells, fibroblasts and myofibroblasts [ 28 29 ] . Keloid fibroblasts demonstrate aberrant apoptotic behavior [ 30 31 ] although studies have given variable results [ 5 9 11 30 31 32 33 34 35 ] . Our initial data for serum-starvation-induced apoptosis in monolayer cultures of dermal fibroblasts demonstrated delayed apoptosis of keloid fibroblasts and a negative correlation with α-SMA expression [ 36 ] . Similar correlations were observed in rat lung fibroblasts, where TGFβ1 increased α-SMA content while acting as an antiapoptotic agent [ 37 38 ] . It should be noted however, that many of the myofibroblasts were still able to undergo apoptosis consistent with in vivo data on palatal wound healing [ 39 ] . Thus, TGFβ1 can promote both α-SMA expression in the initial stages of wound healing and apoptosis in later stages of wound healing.
The reduction in cellularity occurs through the process of apoptosis in fibroblasts [ 28 ] and possibly myofibroblasts ( [ 29 ] , and see below).
However, during granulation tissue remodeling in vivo, decreased cellularity may be the result of apoptosis of fibroblasts and myofibroblasts [ 29 ] .
Resolution of normal dermal wound healing requires a decrease in scar cellularity so as to prevent excessive collagen accumulation and wound contraction.
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