Words similar to cellular
Example sentences for: cellular
How can you use “cellular” in a sentence? Here are some example sentences to help you improve your vocabulary:
In vivo studies have supported the conclusion that CBP/p300 are components of the hormonal-regulation of transcription in fibroblasts isolated from a p300-/- mouse; and loss of the p300 gene severely affects retinoic acid (RA)-dependent transcription [ 91 ] . In a separate study using hammerhead ribozymes that specifically cleave CBP or p300 mRNA, Kawasaki et al [ 92 ] reported that reduced cellular CBP or p300 levels resulted in compromised expression of endogenous RA-inducible genes such as p21/Waf1 and p27 cdk inhibitors.
Both Buchnera and small-genome pathogens show reduction in numbers of genes in many functional categories, including biosynthesis of metabolic intermediates, basic cellular processes (transcription, translation, replication, cell division), biosynthesis of phospholipids, and repair and recombination.
The RNA genome of RSV is about 15 kb long and contains 11 documented protein-coding genes [ 13 ] . Three viral proteins are minimally required to reconstitute the functional transcription complex of NNR viruses [ 3 ] : the nucleocapsid protein (N) that wraps the negative-strand genome RNA and its full-length complement, the positive-strand antigenome RNA, thus converting them into highly nuclease-resistant, chromatin-like templates; the large protein (L), which is the major subunit of the RdRP; and the phosphoprotein (P), which is the smaller subunit of RdRP and an essential transcription factor of L [ 19 20 21 22 ] . In RSV, optimal transcription, although not replication, additionally requires the transcription antitermination protein M2-1 [ 13 ] . In addition, cellular actin, and to a lesser extent, profilin, are also required for viral transcription [ 17 18 ] .
These key events require alterations in the expression of many genes, translation of RNA transcripts, and cellular activation by growth factors, hormones and proteins in the evolving tumor cell population [ 1 2 3 4 5 ] .
In summary, this work extends our view of post-transcriptional control of gene expression by revealing that multiple transcripts involved in cellular regulation associate with the actin cytoskeleton.
Loading...