Words similar to cefoxitin
Example sentences for: cefoxitin
How can you use “cefoxitin” in a sentence? Here are some example sentences to help you improve your vocabulary:
In studies with cefoxitin, cefaclor, and cephalothin as substrate, the observed k cat values for the S224A and S224K mutants were 2- to 7-fold lower; however, the k cat values when using nitrocefin as substrate were slightly higher (< 2-fold).
The I164A mutant exhibited increased K m values only when using cefoxitin as the substrate, suggesting an interaction of the isoleucine group with the methoxy group on cefoxitin.
The changes in molar absorptivities (Δε) used to quantitate products were (in M -1cm -1): nitrocefin, Δε 485 = 17,420; cephalothin, Δε 265 = -8,790; cefoxitin, Δε 265 = -7,000; cefaclor, Δε 280 = -6,410; imipenem, Δε 300 = -9,000; meropenem, Δε 293 = -7,600; biapenem, Δε 293 = -8,630; ampicillin, Δε 235 = -809; and penicillin G, Δε 235 = -936.
When using the cephalosporins, nitrocefin, cefoxitin, and cephalothin, as substrates and the I164A mutant, there were 2- to 10-fold (only for cefoxitin) increases in K m and 2- to 4-fold increases in k cat observed (Table 3).
In kinetic studies using substrates with low K m values (cefoxitin, nitrocefin, and cephalothin) or with small Δε values (penicillin and ampicillin), we typically used substrate concentrations varied between ~ K m and 10 × K m and used as much of the ΔA versus time data (that was linear) as possible to determine the velocity.