Words similar to cefoxitin
Example sentences for: cefoxitin
How can you use “cefoxitin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cefaclor, cefoxitin, and cephalothin were purchased from Sigma; penicillin G and ampicillin were purchased from Fisher.
In studies with cefoxitin, cefaclor, and cephalothin as substrate, the observed k cat values for the S224A and S224K mutants were 2- to 7-fold lower; however, the k cat values when using nitrocefin as substrate were slightly higher (< 2-fold).
The changes in molar absorptivities (Δε) used to quantitate products were (in M -1cm -1): nitrocefin, Δε 485 = 17,420; cephalothin, Δε 265 = -8,790; cefoxitin, Δε 265 = -7,000; cefaclor, Δε 280 = -6,410; imipenem, Δε 300 = -9,000; meropenem, Δε 293 = -7,600; biapenem, Δε 293 = -8,630; ampicillin, Δε 235 = -809; and penicillin G, Δε 235 = -936.
When using the cephalosporins, nitrocefin, cefoxitin, and cephalothin, as substrates and the I164A mutant, there were 2- to 10-fold (only for cefoxitin) increases in K m and 2- to 4-fold increases in k cat observed (Table 3).
The I164A mutant exhibited increased K m values only when using cefoxitin as the substrate, suggesting an interaction of the isoleucine group with the methoxy group on cefoxitin.