Example sentences for: cascades

How can you use “cascades” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • LPS binds to pathogen-associated-molecular-pattern innate immune receptors, such as CD14 and Toll-like receptor 4, activating signal cascades involving NF-κB and MAPK [47] and thereby inducing the transcription and secretion of early cytokines, including TNFα and IL-1 [48].

  • However, in some cell types, ceramide production has been placed at the top of molecular ordering schemes for several signaling cascades as well as increase in reactive oxygen species.

  • Glucose also leads to advanced glycation end products, which initiate free radical cascades and are toxic to cells, including β-cells [ 27 28 ] .

  • The 5-HT 2C receptor activates multiple signal transduction cascades in vivo and in heterologous expression systems (see Raymond et al 2001 [ 22 ] ; and Gerhardt and van Heerikhuizen, 1997 ( [ 5 ] , for reviews).

  • Thus, IL-1β activation of collagenase gene expression requires the increased expression of a panel of essential transcription factors and signaling intermediates, as well as the initiation of signaling cascades that activate these factors.


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