Words similar to carboxyterminus
Example sentences for: carboxyterminus
How can you use “carboxyterminus” in a sentence? Here are some example sentences to help you improve your vocabulary:
This effect requires the aminoterminus of DFz2, implying a requirement for binding Wg to the Fz CRD, but not the carboxyterminus, suggesting that the signal may be, in part, transmitted through an interaction of Wg-Frizzled complex with another protein.
In this experiment, a Wg plasmid activated the luciferase reporter only 12-fold above the vector control; wild-type DFz2 plasmid alone stimulated luciferase levels 7-fold, but neither deletion mutant of DFz2 had any effect, consistent with an earlier report that DFz2 with a truncated carboxyterminus fails to induce the expression of Xnr/Siamois [ 21 ] . However, DFz2ΔC stimulated signaling over 700-fold when delivered in concert with Wg, a synergistic effect nearly as strong as observed with wild type DFz2 (nearly 1700-fold in this experiment).
Therefore, the interaction between DFz2 and Dsh does not depend solely on the carboxyterminus of DFz2.
DFz2 reportedly binds to Wg through its CRD domain [ 6 ] , but it is not known which proteins interact with the carboxyterminus or with cytoplasmic loops in the 7-TM region of DFz2 to transduce the signal to the cytoplasmic signaling component Dsh.
If the carboxyterminus of LRP6 can interact with Axin independently of DFz2 and Dsh, it might reduce the cytoplasmic level of Axin and help stabilize β-catenin.
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