Words similar to carboxypeptidase

Example sentences for: carboxypeptidase

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Since the interactions of Ca +2and Mg +2with proteins are difficult to study due to the lack of spectroscopic properties, vanadyl (V IV=O) 2+has been used as a probe of the ligands that compose Mg 2+, Ca 2+, and Mn 2+binding sites of several proteins, including carboxypeptidase [ 16 ] , S-adenosylmethionine synthetase [ 17 18 ] , pyruvate kinase [ 19 20 ] , and F 1 -ATPase [ 21 22 ] . This cation specifically binds to divalent cation binding sites of several enzymes, and in many cases serves as a functional cofactor [ 23 ] . Vanadyl has one axial and four equatorial coordination sites relative to the axis of the double-bounded oxygen, an arrangement that is similar to that for Ca 2+and Mg 2+.
It has been reported that the amino group serves as one of VO 2+equatorial ligands in CF 1 -ATPase [ 21 ] , pyruvate kinase [ 19 20 ] , AdoMet synthetase [ 17 18 ] , and carboxypeptidase [ 16 ] . Thus one amino group from lysine, one carboxyl group from aspartate or glutamate, and two oxygens from the phosphates of ADPNP serve as the equatorial ligands of sCD39 bound VO 2+in the presence of ADPNP.
The observation that deletion mutants lacking all the p24 proteins still show normal trafficking of certain proteins such as carboxypeptidase Y, suggests that there are some protein-trafficking pathways that are unaffected by their absence.