Example sentences for: carboxy-terminal

How can you use “carboxy-terminal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Despite the lack of detectable sequence similarity to 2OG-Fe(II) dioxygenases, these proteins contain a conserved HXH motif and a carboxy-terminal histidine that appear to be equivalent to the metal-chelating HXD and carboxy-terminal histidine of the latter (see above).

  • 10 from C. elegans and CG17807 from Drosophila ) in which an amino-terminal AlkB-like domain is fused to a carboxy-terminal predicted methyltransferase domain.

  • This family includes the Escherichia coli membrane-associated lipoprotein N1pC, and possesses a catalytic domain containing a conserved amino-terminal cysteine and a carboxy-terminal histidine.

  • The differences in conservation pattern between the distantly related ADA2p carboxy-terminal domains and the canonical SWIRM domains suggest that the former are likely to interact with a very distinct set of partners.

  • The highly acidic carboxy-terminal (BRCT) region of BRCA1 has been suggested to play a role in transactivation [ 11 ] . BRCT interacts with BRCA2, Rad51, other tumor suppressing elements, as well as numerous transcription factors, such as RNA helicase A and STAT1 [ 15 16 ] . Recently, it has been discovered that truncation of this region resulted in suppression of apoptosis following pro-apoptotic stimuli [ 17 ] . Further, these studies also suggested that the BRCT region facilitates apoptotic functions within the caspase pathway.


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