Words similar to cap-independent

Example sentences for: cap-independent

How can you use “cap-independent” in a sentence? Here are some example sentences to help you improve your vocabulary:

The increase in p27 Kip1is mediated, at least in part, by enhanced synthesis of the protein and corresponds to activation of the p27 Kip1mRNA 5'-untranslated region (UTR) and its ability to mediate cap-independent initiation of translation.
The second cistron, encoding luciferase, is downstream of the CAT stop codon and therefore must be translated by a cap-independent mechanism mediated by sequence elements inserted between the two cistrons.
Thus the full-length human p27 Kip15'-UTR is able to mediate cap-independent translation in a manner similar to that previously shown for the 217 nucleotide sequence of the mouse 5'-UTR [ 28 ] .
It was recently demonstrated that elements within a 217 nucleotide sequence from the 5'-UTR of the mouse p27 Kip1mRNA is able to mediate cap-independent translation of a reporter gene in NIH3T3 and D6P2T cells [ 28 ] . There is a high level of sequence homology between the mouse and human 5'-UTRs and the major transcriptional start site is also conserved [ 29 ] . Therefore it is likely the 5'-UTR of the human p27 Kip1message is also able to mediate cap-independent translation initiation.
One possibility is that the p27 Kip1mRNA is translated through a cap-independent mechanism that does not require eIF4E.