Words similar to cap-independent
Example sentences for: cap-independent
How can you use “cap-independent” in a sentence? Here are some example sentences to help you improve your vocabulary:
The increase in p27 Kip1is mediated, at least in part, by enhanced synthesis of the protein and corresponds to activation of the p27 Kip1mRNA 5'-untranslated region (UTR) and its ability to mediate cap-independent initiation of translation.
It has been shown that expression of p27 Kip1is controlled at the translational level [ 3 26 29 ] and that the p27 Kip15'- UTR is able to mediate enhanced translation rates [ 31 ] . In addition, it was recently reported that the p27 Kip15'- UTR has an internal ribosome entry site that allows cap-independent initiation of translation [ 30 ] . However, none of these reports have utilized the full 5'- UTR that results from transcription initiation at the major start site.
One possibility is that binding of 4EBP-1 to eIF4E releases other initiation factors that are in limited supply but also required for cap-independent initiation.
Part of this can be explained by the fact that the p27 Kip15'-UTR is able to promote cap-independent translation.
The second cistron, encoding luciferase, is downstream of the CAT stop codon and therefore must be translated by a cap-independent mechanism mediated by sequence elements inserted between the two cistrons.