Words similar to cancers
Example sentences for: cancers
How can you use “cancers” in a sentence? Here are some example sentences to help you improve your vocabulary:
These included the findings that lung cancers detected by sputum cytology only, compared to chest X-ray only, had a higher rate of complete resectability (83% vs. 62%) and a higher 5-year survival rate (80% vs. 40%) [ 33]; that approximately one-third of the cancers detected by sputum cytology were adenocarcinomas and two-thirds were squamous cell carcinomas [ 32]; that sputum cytology detected 36% of all incident cases of lung cancer (excluding interval cases) [ 32]; and that sputum cytology detected 6/40 adenocarcinomas [ 32].
We have previously demonstrated the overexpression and hormone-independent activation of the IGF-IR in primary breast cancers [ 42 ] . Similar overexpression of the IGF-IR and the ligands IGF-I and IGF-II have been seen in human gliomas and astrocytomas [ 43 44 45 46 ] . Because of the important role for the IGF-IR in cell survival, we investigated whether a dominant negative IGF-IR could inhibit growth of the U87 glioma.
A high prevalence of 3q amplification has been reported in many studies on tobacco-associated cancers, including those of the lung, cervix and esophagus [ 11 13 14 15 16 17 ] . We and others have shown that PIK3CA is a candidate oncogene at 3q in these tumors [ 12 18 19 ] . Interestingly, PI3K pathway has been suggested to play a role in modulating the effects of benzopyrene, a tobacco-derived carcinogen, and its metabolite, anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-terahydrobenzopyrene [ 20 ] .
Vallencian and colleagues biopsied 100 consecutive men with normal or non-suspicious digital rectal examinations and detected only 14 cancers, none with PSA levels below 10 ng/ml [ 29 ] . The Gann study provided the least biased estimate of sensitivity and specificity, but even these results were limited because asymptomatic cancers would not have been detected [ 24 ] . Additionally, serum was stored for about 10 years and PSA is not completely stable [ 30 31 ] .
Estrogen and progesterone, which stimulate the growth of breast epithelium, are two crucial hormones involved not only in normal breast development but also in carcinogenesis of breast epithelium and progression of breast cancer [ 28 ] . About 40% of breast cancers are ER-negative [ 28 ] . ER-negative tumors are unresponsive to anti-estrogen therapy, probably because of constitutive growth factor expression [ 28 29 ] . In general, these tumors have a higher histologic grade and a higher proliferative rate and are associated with poorer prognosis [ 28 ] . The finding that 100% of ER-negative tumors expressed BP1 might therefore be highly relevant to both the prognosis and therapy of those difficult-to-treat tumors.
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