Example sentences for: canalization

How can you use “canalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Recent theoretical work has suggested that canalization may be an emergent property of complex gene networks and may not require specific mechanisms of protein stabilisation and environmental coupling such as those provided by Hsp90 (Siegal and Bergman 2002).

  • have suggested that Hsp90 (heat shock protein 90), a member of a family of proteins expressed at high temperatures (heat shock), may be an excellent candidate for bringing about canalization (Rutherford and Lindquist 1998; Queitsch et al.

  • Hsp90 may not, however, be uniquely placed to act as an evolutionary buffer producing canalization.

  • Clearly, such a mechanism would have important evolutionary consequences; because natural selection acts upon phenotypic variation within a population, canalization first appears to reduce the evolvability of the trait upon which it is acting (Gibson and Wagner 2000).

  • Studying canalization in ion channel gene networks may have significant advantages over studying developmental gene networks because it is relatively straightforward to measure the amounts of ion channels expressed in single identified neurons, to alter the expression of individual ion channels, and to relate these alterations to behaviour.


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