Words similar to canalization
Example sentences for: canalization
How can you use “canalization” in a sentence? Here are some example sentences to help you improve your vocabulary:
have suggested that Hsp90 (heat shock protein 90), a member of a family of proteins expressed at high temperatures (heat shock), may be an excellent candidate for bringing about canalization (Rutherford and Lindquist 1998; Queitsch et al.
However, canalization also reduces the effects of new mutations (which may be deleterious), potentially allowing individuals to store this genetic variation without suffering the consequences.
If canalization breaks down due to genetic or environmental circumstances, then the stored genetic variation will be released, providing an additional substrate for natural selection.
Clearly, such a mechanism would have important evolutionary consequences; because natural selection acts upon phenotypic variation within a population, canalization first appears to reduce the evolvability of the trait upon which it is acting (Gibson and Wagner 2000).
Studying canalization in ion channel gene networks may have significant advantages over studying developmental gene networks because it is relatively straightforward to measure the amounts of ion channels expressed in single identified neurons, to alter the expression of individual ion channels, and to relate these alterations to behaviour.