Example sentences for: camptothecin

How can you use “camptothecin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This assay measures the ability of TOP1 to cleave end-labeled DNA substrates in the presence of the anticancer drug camptothecin, which blocks the ligation step of the cleavage /religation reaction of TOP1.

  • Murine L929 fibroblasts and monkey kidney COS7 fibroblasts were cultured as previously described [ 10 ] . Staurosporine, daunorubicin, actinomycin D, camptothecin and DAPI were from Calbiochem (San Diego, CA), Sigma (St.

  • However, there were no significant differences among these cells in the extent of death caused by staurosporine, actinomycin D, daunorubicin and camptothecin (data not shown).

  • It is evident, however, that cell culture maturation increased resistance to camptothecin treatment.

  • Since CPT analogues become one of the most promising new classes of antineoplastic agents introduced into the clinic in recent years [ 19 ] , activity of camptothecin on endothelial cells may be of great interest.


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