Example sentences for: camp-stimulating

How can you use “camp-stimulating” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Expression of this G S -coupled cAMP-stimulating PGE 2 receptor in cultured vascular smooth muscle cells isolated from the aorta supports a direct role of the EP 2 receptor in mediating vascular relaxation.

  • It has been previously shown that PGE2 not only directly dilates renal arteries [ 9 10 11 ] but also attenuates the AngII-induced increase in renal vascular resistance [ 12 ] through inhibition of AngII-elicited intracellular Ca ++increase in vascular smooth muscle cells of preglomerular vasculature [ 13 ] . Based on the fact that PGE2 stimulates cAMP generation in freshly isolated preglomerular renal arterioles [ 14 ] , the cAMP-stimulating EP2 or EP4 receptor has been thought to mediate these effects of PGE2 on renal resistance vessels.

  • This is in agreement with previous studies which demonstrate that EP 2 is expressed and highly regulated in uterine luminal epithelium cells by ovarian steroids during the peri-implantation period [ 5 21 34 35 ] . The change in level of the EP 2 receptor expression in the uterus may contribute to the increase in G S protein content and cAMP concentration in mid-gestation and the decrease at term [ 26 27 ] . Because the EP 2 receptor is a G S -coupled cAMP-stimulating receptor, the EP 2 receptor may participate in the physiological regulation of uterine relaxation during pregnancy and the transition into uterine contraction at the onset of the labor.


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